HIV pre-exposure prophylaxis information for health professionals

Access to the suite of human immunodeficiency virus (HIV) prevention technologies, including pre-exposure prophylaxis (PrEP) for HIV, is critical to achieving Australia’s goal of virtually eliminating HIV transmission by 2020.

PrEP for HIV is now listed on the Pharmaceutical Benefits Scheme (PBS) as a General Schedule item (Streamed Authority) including medical practitioners and nurse practitioners.

To be eligible for PrEP for HIV, individuals must be at medium to high-risk of HIV infection, as defined by the Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine (ASHM) HIV Pre-exposure Prophylaxis: Clinical Guidelines, and individuals must have a negative HIV test result prior to treatment.

Australian residents with a current Medicare card and a prescription for PrEP from their medical practitioner or or nurse practitioner may access PrEP from a community pharmacy. Individuals without a Medicare card may purchase HIV PrEP at full cost in Australia or from overseas under the Therapeutic Goods Administration (TGA) personal importation scheme.

ASHM clinical guidelines

South Australian health practitioners should refer to the ASHM HIV Pre-exposure Prophylaxis Clinical Guidelines. The ASHM HIV PrEP Guidelines outline behavioural risk and eligibility criteria for men who have sex with men (MSM); heterosexual men and women; trans and gender diverse people; and people who inject drugs.

In addition to assisting clinicians in assessing eligibility of patients for PrEP, the ASHM HIV PrEP Guidelines provide guidance on commencing and monitoring patients on PrEP including management of side-effects and toxicity, use of PrEP in pregnancy and in chronic hepatitis B infection; daily and on-demand (also known as event-based) PrEP dosing; and discontinuing PrEP.

The ASHM HIV PrEP Guidelines provide a recommended appointment schedule of testing and ongoing monitoring for health practitioners managing individuals accessing PrEP for HIV.

Decision making tool

A two-page Decision Making in PrEP: Prescribing Pathway for PrEP in Australia tool summarises the eligibility criteria and recommended assessment for primary care providers in Australia who wish to prescribe PrEP and as well as patient education and monitoring requirements.

Experienced clinicians in South Australia

To contact a clinician with experience in prescribing PrEP in South Australia, please contact the Adelaide Sexual Health Centre.


For information on PrEP for HIV training courses, visit the Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine (ASHM)